1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate
Propetamphos
CAS: 31218-83-4
Molecular Formula: C10H20NO4PS
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Names and Identifiers
| Name | Propetamphos |
| Synonyms | Blotic Safrotin Propetamphos 1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate 1-methylethyl (2Z)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate |
| CAS | 31218-83-4 |
| EINECS | 250-517-2 |
| InChI | InChI=1/C10H20NO4PS/c1-6-11-16(17,13-5)15-9(4)7-10(12)14-8(2)3/h7-8H,6H2,1-5H3,(H,11,17)/b9-7- |
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Physico-chemical Properties
| Molecular Formula | C10H20NO4PS |
| Molar Mass | 281.31 |
| Density | 1.15g/cm3 |
| Melting Point | <25℃ |
| Boling Point | 321.1°C at 760 mmHg |
| Flash Point | 148°C |
| Water Solubility | 110 mg l-1(24°C) |
| Vapor Presure | 0.000304mmHg at 25°C |
| Appearance | morphology neat |
| pKa | 0.94±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.494 |
| Physical and Chemical Properties | Chemical properties light yellow oily liquid. Boiling point 87-89 ℃(6.65 × 10-4kPa), relative density 1.1294(20/4 ℃), refractive index 1.495. The solubility in 24 ℃ water is 110mg/L, which is soluble in most organic solvents. Stable to heat and light. |
| Use | Has the effect of killing and stomach poison, mainly used to control cockroaches, flies and mosquitoes and other pests |
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S37 - Wear suitable gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | 3018 |
| WGK Germany | 3 |
| RTECS | GQ4750000 |
| HS Code | 29299090 |
| Hazard Class | 6.1(b) |
| Packing Group | II |
| Toxicity | LD50 orally in male rats: 82 mg/kg (Berg, Gothe) |
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Upstream Downstream Industry
| Raw Materials | o-Xylene Methyl alcohol thiophosphoryl chloride |
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Nature
| Merck | 13,7907 |
| BRN | 1979853 |
| EPA chemical information | Propetamphos (31218-83-4) |
Last Update：2024-04-10 22:29:15
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Uses and synthesis methods
use
1. alkylene phosphorus is a contact insecticide, which is used for stomach toxicity. It can effectively control cockroaches, flies, mosquitoes and other pests, as well as cow lice.
2. It has contact and stomach poison effects, mainly used to control pests such as cockroaches, flies and mosquitoes
production method
In the presence of catalyst and acid binding agent, the intermediate obtained by the reaction of 3-hydroxybutenoic acid isopropyl ester and thiophosphoryl chloride is condensed with methanol and ethylamine to obtain alkylene phosphorus. In industrial production, tributylamine is added to the mixture of isopropyl acetoacetate and thiophosphoryl chloride, stirred and cooled at -3 ℃ during feeding, continued to stir at 0-3 ℃ for 4.5h, separated viscous oily liquid, added toluene and petroleum ether, filtered out tributylammonium chloride, the filtrate is concentrated in vacuum at a bath temperature of 30 ℃, methanol is added to the residue, reduced to 0 ℃ as quickly as possible, the feeding temperature is -5 ℃, mixed at 0 ℃ and stirred for 4.5h. The reaction mixture is extracted twice with about 10% hydrochloric acid solution. Adding petroleum ether during the second extraction is conducive to extraction. The petroleum ether is washed with water and alkali, and dried with anhydrous sodium sulfate to remove the solvent to obtain alkylene phosphorus. Raw material consumption quota: tributylamine 670kg/t, isopropyl acetoacetate 520kg/t, phosphoryl chloride 650kg/t, methanol 470kg/t, ethylamine (70%)820kg/t.
Last Update：2024-04-10 22:29:15
1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate - Security information
| toxic substance data | 31218-83-4(Hazardous Substances Data) |
Last Update：2024-04-09 01:59:50
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Product Name: Propetamphos；PROPETAMPHOS Request for quotationCAS: 31218-83-4
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Multiple Specifications
Product Name: Propetamphos Visit Supplier Webpage Request for quotationCAS: 31218-83-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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Raw Materials for 1-methylethyl (2E)-3-{[(ethylamino)(methoxy)phosphorothioyl]oxy}but-2-enoate